As artificial intelligence moves rapidly into clinical, operational, and consumer-facing use, healthcare leaders are navigating a fast-evolving governance landscape shaped by federal guidance, executive orders, and a growing wave of state-level legislation. This session explores how policymakers, regulators, and health systems are balancing innovation with accountability, transparency, and risk management—covering clinical AI, payer use cases, chat bots, and emerging regulatory “sandboxes.” Panelists will discuss what effective AI governance looks like in practice and the implications for adoption, oversight, and reimbursement as organizations scale AI responsibly.